POLYNUCLEOTIDES | LEEDS
Polynucleotides
The Next Generation of Injectable Skin Rejuvenation.
Polynucleotide injections deliver something truly different. Rather than adding volume like traditional dermal fillers, this treatment activates your skin’s own repair mechanisms. Specifically, it targets free radicals, boosts deep hydration and promotes genuine tissue regeneration for visibly healthier, more resilient skin.
Crafted from purified fragments of DNA, polynucleotides stimulate fibroblast activity — the cells responsible for producing fresh collagen and elastin. As a result, your skin behaves the way it did in younger years. Moreover, the treatment offers powerful anti-inflammatory and antioxidant benefits that improve skin texture, tone and elasticity over time.
Park Square Clinic brings this innovative treatment to Leeds with the precision and care you’d expect from a medical-led clinic. Of course, every treatment begins with a thorough consultation. That way, we can tailor your polynucleotide treatment plan to your individual skin concerns and goals.
Treatment Length
30 minutes
Number of Sessions
3 sessions recommended
Duration of Results
6–12 months
Downtime
Minimal
Your Skin, Regenerated From Within.
What makes polynucleotides so remarkable? They don’t simply treat the surface. Instead, these injectable bio-stimulators work at a cellular level, sending biological signals that trigger your skin to produce new collagen and elastin naturally.
In particular, polynucleotides activate a pathway that reduces inflammation and improves microcirculation. Consequently, your skin receives better nourishment from within. The result is skin that looks and feels genuinely healthier, with improved texture, tone and hydration.
Furthermore, polynucleotides are effective in delicate areas where other treatments simply cannot reach — including under the eyes, the forehead and the lips. Whether you’re looking to reduce fine lines, diminish dark circles or restore a brighter, more youthful complexion, this treatment delivers high-impact results in the softest, most natural way.
What are Polynucleotides?
Polynucleotides are an injectable bio-stimulator consisting of stretchy molecules crafted from purified fragments of salmon DNA — selected for its remarkable similarity to human DNA. Unlike traditional dermal fillers that predominantly add volume, polynucleotide injections enhance the quality of your skin itself.
The treatment works by stimulating collagen and elastin production in your skin’s cells. Initially, polynucleotides act as wound healing agents, prompting intensive skin repair. This reduces scar tissue, smooths uneven texture and promotes cell renewal. In addition, their anti-inflammatory properties calm sensitive or reactive skin while boosting deep hydration.
The Gold Standard in Skin Regeneration
Developed using highly purified polynucleotide technology, this treatment has been recognised as one of the most advanced bio-regenerative solutions in aesthetic medicine today. Published clinical research confirms that polynucleotide injections significantly improve skin hydration, elasticity and texture. Importantly, polynucleotides gradually dissipate after activating regeneration rather than remaining in place indefinitely — delivering natural, lasting improvement without artificial residue.
Areas We Treat with Polynucleotides in Leeds
Polynucleotide injections are remarkably versatile. At Park Square Clinic, we use them to treat a wide range of areas where skin quality, texture and firmness need restoring.
Face & Delicate Areas
- Face (full facial rejuvenation)
- Under the eyes (dark circles and hollowness)
- Forehead and temples
- Lips and perioral area
Body Areas
- Neck and decolletage
- Hands
- Scarring and stretch marks
Whether you are addressing early signs of ageing or looking to restore skin that has lost its vitality, polynucleotides offer a targeted, natural solution. Book a consultation at Park Square Clinic in Leeds to discover how this treatment can work for you.
FAQs
FAQs
- What are polynucleotides?
Polynucleotides are an injectable bio-stimulator made from purified fragments of salmon DNA, chosen for its close similarity to human DNA. Unlike traditional fillers that add volume, polynucleotides enhance your skin quality itself by targeting free radicals, boosting hydration and stimulating tissue regeneration at a cellular level.
- How do polynucleotide injections work?
Polynucleotide injections stimulate fibroblast activity in your skin cells, triggering the production of new collagen and elastin. Initially, they act as wound healing agents that prompt intensive skin repair. In addition, they possess anti-inflammatory properties that promote cell renewal, improve elasticity and boost deep hydration. The polynucleotides gradually dissipate after activating regeneration, rather than staying in the skin indefinitely.
- What areas can be treated with polynucleotides?
Polynucleotides can be used on the face, under the eyes, forehead, temples, lips, neck, decolletage, hands, and areas with scarring or stretch marks. They are particularly effective in delicate areas like under the eyes where other treatments may not reach.
- How many sessions will I need?
We typically recommend three polynucleotide sessions, spaced approximately one month apart. For ongoing maintenance, a top-up every 9 to 12 months helps maintain results. However, this depends on your individual concerns and treatment area. Your practitioner will create a tailored plan during your consultation.
- When will I see results from polynucleotide treatment?
Polynucleotides continue to stimulate the treatment area for up to 12 weeks following each session, so results develop gradually. For the face and neck, improvements in skin quality and elasticity typically become visible after a few weeks. Under-eye results are often noticeable sooner. Full results build over the course of your treatment plan.
- Is there any downtime after polynucleotide treatment?
Downtime is minimal. As with most injectables, you may experience slight swelling or bruising at the injection sites. This is typically mild and temporary, resolving within a day or two. Your practitioner will talk you through aftercare at your appointment.
- Are polynucleotides suitable for all skin types?
Polynucleotides are suitable for most skin types and can benefit a wide range of concerns, from early signs of ageing to more advanced skin laxity. However, a consultation is essential to assess your skin and confirm suitability. At Park Square Clinic in Leeds, we always carry out a thorough assessment before recommending any treatment.
- Are polynucleotides the same as dermal fillers?
No. Polynucleotides are fundamentally different from dermal fillers. Fillers typically contain hyaluronic acid and add volume beneath the skin. Polynucleotides, on the other hand, consist of biopolymers derived from DNA fragments. They work by stimulating your skin’s own regeneration process rather than filling. That said, polynucleotides can complement fillers beautifully for both immediate and long-term enhancement.
- Can polynucleotides be combined with other treatments?
Absolutely. Polynucleotides can be seamlessly integrated with other skin booster treatments such as Profhilo, as well as energy-based treatments and dermal fillers. Combining polynucleotides with complementary treatments can deliver exceptional results. Your practitioner will advise on the best combination and timing for your personalised plan.
- Are polynucleotide injections safe?
Polynucleotide injections have an excellent safety profile. Side effects are generally mild and transient — typically limited to slight swelling or bruising. The treatment uses purified biological material with high biocompatibility. At Park Square Clinic, all treatments are administered by experienced, medically trained practitioners in a clinical setting. Your safety and comfort are always our priority.
